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cobicistat will enhance the degree or effect of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Carefully. A decreased dose of diazepam can be requiredObserve Closely (1)oxcarbazepine will decrease the extent or effect of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism.Reserve concomitan